Emerson Exchange 365
Blogs
    • 17 Apr 2018

    Technology Trends for Life Sciences Manufacturers

    We seem to be fully in the swing of industry conferences. This week is the pharmaceutical and biotech manufacturing industries’ INTERPHEX conference in New York City. It: …brings over 11,000 global industry professionals and 650+ leading suppliers together to “Learn It, Experience It, Procure It” through a combination of no cost technical conference, exhibits, demonstrations, and networking events...
    • 13 Mar 2018

    Data Integrity for Pharmaceutical and Biotech Manufacturers

    For pharmaceutical, biotech and other manufacturers in highly-regulated industries, the production data is as important as the product itself for release to sale. Data integrity of this production data is paramount. I connected with Emerson’s Michalle Adkins about what manufacturers are doing to assure this data is accurate and timely. She shared with me some key regulatory standards and best practices. Michalle...
    • 20 Feb 2018

    Identify and Resolve Cell Therapy Batch Manufacturing Exceptions

    We conclude our series on improving cell therapy manufacturing with a closer look at the review by exception process. In the manufacturing process of cell therapeutics, product cycle times are extremely short and any exceptions occurring during the production process must be found and addressed quickly. Emerson’s Bob Schiros notes that manufacturing execution systems, such as the Syncade MES , must include...
    • 13 Feb 2018

    Increasing Autoclave Reliability via Machine Learning Technology

    ARC Advisory Group’s Paula Hollywood moderated a session, IT/OT/ET Convergence at the 2018 ARC Industry Forum. Here’s the description from this session: The convergence of IT (Information Technology at the enterprise level) and OT (Operations Technology, the information and automation technologies employed in the plant), is not new, but the relationship is intensifying. What is changing is the addition...
    • 7 Feb 2018

    Designing and Building Pharmaceutical and Biotech Smart Factories

    Pharmaceutical and biotech manufacturers seek to improve both project and operational performance through implementation of smart factory technology. The smart factory fits right into the S95 enterprise automation model and provides out-of-box manufacturing functionality representing the best practice in the industry and complying with the regulation such as cGMP. The smart factory technology connects the plant digitally...
    • 2 Feb 2018

    Digital Transformation to Paperless Production

    Manufacturing processes have long been paper-based with log entries, initialing, signoffs and other transactions to manually record. While automation systems have captured some of this manual recordkeeping, they have not been able to capture everything. In batch manufacturing processes that produce thousands of batches each year, maintaining paper records for each batch is a time-consuming, error-prone, and costly...
    • 18 Jan 2018

    Reducing Execution Errors in Cell Therapeutics Manufacturing

    In an earlier post, Managing the Chain of Identity in Cell Therapeutics Manufacturing , we highlighted how the manufacturing process of these cell therapies must be performed with absolute accuracy the first time since each batch is produced for a specific patient. It’s critical during the production process that any execution errors be identified and corrected before completion. Any errors in development, manufacturing...
    • 17 Jan 2018

    Digital Twin for Increased Project and Operational Performance

    You may have been seeing the phrase “Digital Twin” more and more in the automation and industry press. Wikipedia defines the Digital twin concept as: …a digital replica of physical assets, processes and systems that can be used for various purposes. [1] The digital representation provides both the elements and the dynamics of how an Internet of Things device operates and lives throughout its life cycle...
    • 4 Jan 2018

    Managing the Chain of Identity in Cell Therapeutics Manufacturing

    Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. From a manufacturing perspective, each therapeutic batch must be perfect the first time — because each batch is produced for a specific patient. The next unique batch, for...
    • 4 Jan 2018

    Managing the Chain of Identity in Cell Therapeutics Manufacturing

    Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. F...