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  • Effective Personnel Drive Operational Integrity

    As consumers of medicinal products of various kinds (vaccines, immunotherapies, tablets, capsules, cell therapies, etc.), we know that although product quality is important, reliable supply is also critical. A reliable supplier of therapeutic goods requires the facilities within its manufacturing supply chain to also be reliable suppliers of their intermediates and products. An important part of being a reliable supplier…
  • Avoid Taking a Successful Reliability Program for Granted by Improving Its Use

    Success must be supported so it can be sustained. As Chris Jensen and H.P. Slater discuss in an article in the July issue of Process Heating , this line of thinking is no less true in predictive maintenance (PdM) than in anything else. Some companies are impressed with the initial savings that PdM programs generate through improved production and lower maintenance costs, but New PdM programs typically identify many…
  • Avoiding Unplanned Downtime in Life Sciences Industry

    For manufacturers in the Life Sciences industry, production challenges often occur in these four areas—production readiness, equipment reliability, personnel effectiveness and facility/line efficiency. In this post, I’ll focus on equipment reliability, and specifically, unplanned downtime. Maintenance Scheduling Click to enlarge Equipment reliability spans several areas—asset performance, line and unit performance…
  • Improve the Flow, then Automate

    Digital technology amplifies process outcomes, both good and bad, by automating standard workflows, completing calculations, and performing repetitive tasks. It provides the ability to capture and analyze process data real-time while leveraging predictive modeling to inform rapid decision making. Once installed and validated, digital technology relentlessly enforces predetermined process standards. It provides valuable…
  • Fast Tracking Adaptable Manufacturing in Life Sciences

    To inoculate people worldwide as soon as vaccines are proven requires the pharmaceutical industry to ramp up quickly to unprecedented volumes of supply. And technology transfer—moving the knowledge about and the ability to produce a vaccine from development to manufacturing—is a primary determinant of how fast it happens. In a presentation at the ACHEMA Pulse virtual conference this year, Emerson’s Alan Johnston shared…
  • Digital Transformation Key to Vaccine Development and Rollout

    The first doses of a Covid-19 vaccine were administered on Dec 14, 2020, about a year after the disease was first detected. Tested, FDA-approved for emergency use, rapidly manufactured and safely delivered at sub-freezing temperatures, this was, by any measure, the fastest pathway to vaccination in human history. One of the latest examples of development from scratch was the mumps vaccine in the 1960s. It took four…
  • Rosemount 1408H Non-Contacting Level Transmitter Receives Red Dot Design Award

    The Red Dot Design Award is an annual design competition that appraises the best products created every year. Expert juries in the areas of product design, communication design, and design concepts, select the winning designs. The Rosemount 1408H Non-Contacting Level Transmitter has received the award for Product Design 2021 and has been acknowledged for its stylish, innovative and patented cooling design, which allows…
  • Improving Logical Changeover Production Readiness in the Life Sciences

    Pharmaceutical and biopharmaceutical manufacturers have long felt the pressures of moving products from discovery to delivery as fast as they can—even given the highly regulated industry in which they operate. Technology has continued to advance and provide ways to assist these companies with production readiness. Improper set up and qualification of automation and information management production applications cause…
  • Breakthroughs in Bioprocess Modeling and Control

    Biopharmaceutical manufacturers have done amazing work in getting the COVID-19 vaccines out across the globe. Bioprocessing of these and other medicines is performed in bioreactors which rely on cells to create the intended therapeutic. Emerson’s Greg McMillan , teaming with Christopher Stuart , Rehman Fazeem , Zachary Sample and Timothy Schieffer have updated and revised the second edition of the book, New Directions…
  • Five Things You Can Do, Starting Today, to Improve Your Cybersecurity Defenses

    Recent world events—from the expansion of remote access in response to COVID restrictions to high-profile industrial cyberattacks—have put a renewed focus on cybersecurity. While cybersecurity needs vary from organization to organization, there are common, critical steps every company can follow to improve their cybersecurity posture.   Alexandre Peixoto and Lee Neitzel explore five of these strategies in automation.com…
  • Rapid Engineered Solutions for Complex Fluid Control Applications

    Time to market is critical for most industries and this is true for medical device & analytical instrumentation manufacturers. Suppliers to these manufacturers need to quickly respond to demands for innovative technologies and expertise to help the manufacturers meet their aggressive project schedules. In this 3-minute YouTube video, Rapid Engineered Solutions Customized Analytical & Medical Valve Solutions , Emerson…
  • Precision Miniature Isolation Valves in Clinical Diagnostic Equipment

    We all appreciate the advances in medical technology to detect issues early and help us lead full and healthy lives. For medical diagnostic equipment that require fluid samples, this equipment requires fast, accurate and compact fluid control during diagnostic test runs. In this 5-minute YouTube video, Fluid Control Solutions for Clinical Laboratory Dispensing Applications , Emerson’s Tony Gaglio describes a new product…
  • Emerson Technologies Supporting Fast COVID-19 Vaccine Development and Rollout

    In a Pharmaceutical Processing World article, Emerson’s Ben Arriola and Zach Blum discuss technologies advancing vaccine development. It’s safe to say that there has never been a pharmaceutical effort so huge, fast, and successful as developing multiple vaccines for COVID-19. It is truly global in that countries all over the world are developing their own formulations. Making this possible and practical has depended…
  • Digital Twin Technology for Bioreactor Control and Optimization

    At Texas A&M University’s Mary Kay O’Connor Process Safety Center’s 76 th Instrumentation and Automation Symposium , Emerson’s Greg McMillan presented two topics. I’ll recap his Bioreactor Control and Optimization presentation in today’s post and save his Process Effects on Control for a future post. Greg opened explaining how digital twin technology enables Process Analytical Technology (PAT) for manufacturers in the…
  • Making Medicine Personal with Flexible Automation Solutions

    Personalized medicine manufacturers are rapidly changing their manufacturing platforms to provide a new scale of production. In the Emerson Exchange Virtual Series, life sciences experts held an open Q&A on the trajectory of cell and gene therapies, and how a different approach to automation helps enable a brave new world of therapeutics. Cell and gene therapies disrupt manufacturing Kelsey Hill , Emerson’s life…
  • Single-Use Biopharma Needs Specialized pH Sensing Technology

    Industry is seeing a shift to single-use biopharmaceutical manufacturing methods, prompting a need for new pH measurement approaches to overcome instrumentation challenges. Scientist working with a bioreactor for cell culture Monitoring and historizing the pH of a process media batch, and often using this value for control and automation, is commonly required for biopharma processing operations. Traditional production…
  • Modular Plug and Play, MTP Will Enable More Flexible Life Sciences Manufacturing

    Modular facilities are a key enabler of speed to market in life sciences. As organizations try to bring new therapies to market faster, those therapies require a wide variety of equipment—many of which are new to the process. These new machines must not only work together, but also must integrate seamlessly with existing process equipment and systems to keep production nimble. In the recent Emerson Exchange Virtual…
  • Digital Transformation Helps Moderna Safely Deliver COVID-19 Vaccine in Record Time

    A common theme across the Emerson Exchange Virtual Series has been the way software and digital technologies have helped us all deal with an unexpected and unprecedented pandemic. Wherever there is adversity, there are also innovators who step up to the challenge of delivering solutions to critical problems. In the February keynote address, Speed to Market, Jim Nyquist , chairman of Emerson’s systems and software business…
  • Precision Flow for Laboratory Instruments

    So, your doctor has ordered a blood or other bodily fluid sample, or you’ve taken a COVID-19 test. What happens to these samples next? In a short 3:11 video, Medical Moment | Clinical Laboratory Instruments | ASCO , Emerson’s Jim Perry and Tony Gaglio address this question and discuss the typical challenges clinical laboratory instruments manufacturers face and how Emerson’s engineers and customized fluid control solutions…
  • Digitalizing and Automating Review by Exception

    Review by exception recordkeeping for pharmaceutical and biopharmaceutical producers collects the critical process exceptions during production runs. Good automated manufacturing practice (GAMP) approach for these electronic production records are: …processes are maintained within defined tolerances, data & events are recorded; process data is monitored at appropriate intervals, alerts and alarms are generated when…
  • Welcome to Emerson Automation Experts Podcasts

    Visit our podcast subscription page to subscribe with your favorite podcast player. The post Welcome to Emerson Automation Experts Podcasts appeared first on the Emerson Automation Experts blog.
  • Artificial Intelligence in Vaccine Manufacturing

    Recently vaccines have become available to help in putting the COVID-19 pandemic behind us. Artificial Intelligence (AI) technologies were used in the race to develop these vaccines. In a Jersey’s Best article, Powerful AI technology is changing the way N.J. operates, for the better , Emerson’s Dennis Belanger explains how AI is used: …as a monitoring tool to understand the condition of eggs that are often used to…
  • Single-Use Pressure Transmitter Receives Pharma Innovation Award

    The annual Pharma Innovation Awards , selected by the editors and reviewers of Pharma Manufacturing , recognize leaders in pharmaceutical equipment and technology for the potential value and innovation they bring to the pharma industry. The Rosemount 550PT Pressure Transmitter was among one of these recently awarded technologies, acknowledged for filling the need for instrumentation technology designed specifically for…
  • Reliable and Stable Bioprocessing Single-Use Sensors

    In an Emerson Exchange Americas Virtual Series presentation, Validating Single-Use Sensor Performance and Integration with Bioreactors, Emerson’s Brandon Haschke highlighted these technologies. Here is the presentation abstract: Single-use technologies are a rapidly growing sector of life sciences manufacturing. These technologies reduce costs in manufacturing and increase a manufacturing facility’s flexibility, allowing…
  • Digital Transformation to Fast-Track Vaccine Development

    Have you wondered how some of the leading pharmaceutical and biopharmaceutical manufacturers have developed and tested their COVID-19 vaccine candidates in record time? In a Pharma Manufacturing article, The new requirement to fast-track vaccines , Emerson group president for the Systems and Software business, Jim Nyquist , shares ways in which these feats were accomplished. A digital transformation was needed to dramatically…