Activity
  • Improving Recipe Management by Implementing FAIR Principles

    BioPhorum recently published an excellent paper, Data governance needs in biomanufacturing: a position paper . This paper proposes adopting the FAIR principles for data management, meaning that data must be F indable, A ccessible, I nteroperable, and R eusable . As stated in the paper: Adopting these principles is a potentially transformational opportunity for the life sciences industry, one that could fundamentally…
  • Exploring the Ways to Improve the Efficiency of Solenoid and Miniature Valves for Homecare and Portable Medical Devices

    By combining the flexibility of new and proven flow-control products with the engineering expertise offered by valve suppliers, control valves for home care medical devi ces can become more efficient than ever before. In this article by Paul Gant, he listed some of the factors to consider in order to control and overcome various challenges and meet the demands needed in the medical industry. One key aspect to consider…
  • Driving Operational Improvements with a Rugged PAT Model Infrastructure

    Real-time manual sampling has been a tried-and-true manufacturing practice for decades. But this antiquated approach has been subject to the risk of human error, time-sensitive, and time-consuming. Today’s digital technologies have enabled manufacturers to automate and improve this process. At the IFPAC-2023 meeting , Emerson’s Bruce Greenwald and Aspen Technology’s Geir Rune Flåten teamed together to present, Deploying…
  • Life Sciences Single-Use Instrumentation Trends

    For most industries, scaling up with large batch sizes and high-volume production equipment is the best way to gain efficiency. This has also been true for production of many life sciences drugs, but portions of the industry are shifting toward creating smaller runs of “personalized drugs,” especially biologics, targeting smaller population segments. In our June 2023 article in Pharmaceutical Processing World , titled…
  • Unshackle Innovation with One Click Tech Transfer

    Most people have heard the adage that, “COVID changed everything.” However, few people, when presented with that idea, think that any of those changes were positive. But we often forget that in the span of eight short months, the world saw a wide array of innovators and manufacturers come together to deliver a vaccine—a process that typically takes upwards of 15 years. In his recent article in Industry Week magazine…
  • Life Sciences Digital Maturity – Know Where You Are to Know Where You Can Go

    To know where you’re going, you have to know where you are, and operating a life sciences manufacturing facility is no exception. Pharmaceutical processors regularly have to take stock of their technological capacity to keep a finger on the pulse of the four main drivers of operational excellence: Pipeline acceleration – the capability to quickly bring new products to market. Flexible manufacturing – maintaining…
  • Prototype Sensing Technologies are at the Forefront of Innovation

    On June 4-7, experts in process analytical technology (PAT) gathered for the 2023 IFPAC conference . While there, they discussed the latest developments in PAT , quality by design, and overall process monitoring and control within the pharmaceutical, biotechnology, food, chemical, petrochemical, and related industries. Once again, Emerson experts were in attendance. Ye Lin and Ben Arriola presented new technologies…
  • Data-Driven Culture Drives Maintenance and Reliability Results

    Life sciences organizations are not short on data. Most plants already have many sensors in place to drive operational data to the control system so operators always know exactly what is happening at any given moment of production. Operations teams know that good data is essential to Good Manufacturing Practice, and, as such, they treat it with the reverence it deserves. In her recent article in Pharmaceutical Processing…
  • Digital Solutions for Process Development, Tech Transfer and Manufacturing

    Last week, IFPAC 2023 was held in Maryland. If you’re unfamiliar with IFPAC, here is a description from their website. IFPAC is the essential meeting place for the latest developments in Process Analytical Technology…PAT, Quality by Design…QbD, and overall process monitoring & control within the Pharmaceutical, Biotechnology, Food, Chemical, Petrochemical & related industries. Emerson’s Michalle Adkins and AspenTech…
  • Traceability Across the Entire Drug Development Pipeline

    Recently, as cell and gene therapies have begun to emerge in the life sciences manufacturing landscape, an important concept has begun to draw attention: traceability. However, it is important to remember that traceability was critical long before today’s most cutting-edge therapies began development. Traceability has been essential in the manufacture of nearly every treatment, both in process definition and in product…
  • Better Treatment—For the Earth, and its People

    It can be hard to keep up with the many rapid changes occurring in the life sciences industry these days. In an effort to embrace improved speed to market, sustainability , and quality, life sciences manufacturers are employing a wide range of software and technologies that only ten short years ago might have been considered science fiction. To help filter these many trends and give readers a glimpse into where the…
  • Four Pillars of Life Sciences Speed to Market

    People are more aware than ever of the many amazing ways new treatments can improve their lives. As a result, life sciences companies are under more pressure than ever to safely deliver new, innovative treatments to market to satisfy customer demand. The key to accelerating that pipeline is based around four pillars of digitalization that Emerson experts Michalle Adkins and Karen Fung share in a recent Q&A in BioPharma…
  • Smart Maintenance Practices in Biopharmaceutical Manufacturing

    As the Industrial Internet of Things enables more and more wireless instrumentation, the ability to transform maintenance practices to become more predictive grows. While companies in several industries have moved to predictive maintenance practices, companies in other sectors have been somewhat slower to adopt them. In a new paper published by the BioPhorum organization, Smart Maintenance Architecture: A Data-Driven…
  • What Is Emerson’s Rapid Engineered Solutions Program?

    Rapid Engineered Solutions help analytical and medical equipment manufacturers accelerate the fluid handling design and engineering phase of new product development. Are you an analytical or medical OEM design engineer struggling with compressed product development timelines? Do you need a rapid solution to complex fluidic system challenges? The Rapid Engineered Solutions program from Emerson is the perfect solution…
  • Embedded Spectral Process Analytic Technology

    Effective quality assurance processes are essential in pharmaceutical and biopharmaceutical manufacturing processes. Deploying Process Analytical Technologies (PAT) is one way these manufacturers have driven business improvements. Pharma Manufacturing magazine’s Pharma Innovation Awards highlights the technologies and systems driving improvements across manufacturing operations. Their December 2022 article, Pharma Innovation…
  • Improving Digital Maturity is Key to Life Sciences Success

    In just the last 10 years, biopharmaceutical supply chains have changed dramatically. The single-source manufacturing model is becoming much rarer, making way for multi-enterprise manufacturing collaborations and partnerships to better meet the changing needs of the life sciences marketplace. In collaboration with other life sciences leaders, Emerson’s Michalle Adkins contributed to a BioPhorum paper outlining a vision…
  • Real-World Implications of Spectral PAT for Life Sciences

    There is a growing buzz around spectral process analytical technology (PAT) for the life sciences industry. Spectral PAT sounds really fancy. What is it, and how can it affect my company’s mission to produce treatments and cures that improve the quality of life for our patients? Let’s start with the basics. The ultimate value proposition of every life sciences manufacturer is to produce goods that dramatically improve…
  • Leverage Life Sciences Software to Reduce Time to Market

    The days of maintaining paper records across the life sciences development and production pipeline are gone. Today’s regulatory requirements, not to mention the complexity of new treatments, requires organization that can only be provided electronically. However, while many life sciences teams have moved to electronic records software , many teams are still inadvertently creating data silos—both horizontally across business…
  • Module Type Package Unlocks the Flexibility Driving Pharma Innovation

    There can be little question that Industry 4.0 technologies are reshaping the way life sciences companies operate. In the wake of the rapid development of vaccines during the COVID-19 pandemic , more facilities than ever are being “born digital.” Some of these born-digital facilities are the result of new organizations with entirely digital strategies, and others are biopharmaceutical organizations that have been around…
  • Let your Personnel Lead you to the Adaptive Plant

    On Monday at the Emerson Exchange Users’ Conference , Emerson’s Michalle Adkins and AbbVie’s Jeff Ziolkowski moderated a panel with Fujifilm’s Soren Skerris , Takeda’s Dr. Nina Schwalb , Eli Lilly’s James Weber , and Emerson’s Christian Berg . The experts shared the strategies they have employed and the lessons they’ve learned on their journey across the BioPhorum Digital Plant Maturity Model toward creating adaptive…
  • Reduce Waste & Increase Efficiency in Clean-in-Place Processes

    While the idea of adding costs to a food and beverage or pharmaceutical industry process like Clean-in-Place/Steam-in-Place (CIP/SIP) has not traditionally been an easy decision, in today’s industrial environment that has changed. With the retirement of experts, the lack of availability of workers, the increase in materials costs and narrowness of margins, the principal way for food and beverage and pharma companies to…
  • New Challenges for Gas Analyzer Designers

    Household waste, industrial emissions, and automobile exhaust are some of the pollutants that can contribute to climate change. They can also make you feel under the weather. In addition, these emissions contribute to the depletion of the Earth’s ozone layer. Due to the threat of these environmental issues, countries around the world have enacted strict legislation aimed at reducing emissions. In the U.S., the EPA…
  • Software Simplifies Technology Transfer

    The life sciences marketplace is changing faster than nearly any other industry. Gone are the days when companies focus on a single treatment to drive their entire business. Today’s life sciences manufacturers are challenged to bring new treatments to the marketplace as quickly as possible—a trend that was magnified during the COVID-19 pandemic . As a result, innovation is key today. And innovation requires technologies…
  • Manufacturing Solutions in Personalized Healthcare

    In our Part 1 post, Manufacturing Challenges in Personalized Healthcare , Emerson’s Christian Berg explored the challenges biopharmaceutical manufacturers face in advancing personalized healthcare. In this final part, he describes some solutions and technologies which facilitate the pursuit of the adaptive plant, as defined by the BioPhorum Digital Plant Maturity Model , required to meet these challenges. Christian…
  • Manufacturing Challenges in Personalized Healthcare

    When we hear the phrase “personalized healthcare,” many of us think about the medicines and therapeutics focused on our specific needs that deliver treatments to dramatically improve or restore our health and extend our lives. In a Pharma Focus Asia webinar, Pursuing the Adaptive Plant to Enable Personalized Healthcare , Emerson’s Christian Berg provides a broader perspective of personalized healthcare and its challenges…