Emerson Exchange 365
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    • 96 posts
    • Updated 11 days ago
Activity
    • 11 Oct 2017

    Integrating Analytics Across Process Development Lifecycle

    For batch processes found in industries such as pharmaceutical & biopharmaceutical, food & beverage, specialty chemicals, etc., analytics technology advancements are helping to improve quality, consistency and reliability. I caught up with Emerson’s Zuwei Jin for an update on these advancements and how they are being applied. He put together a chart of the process analytics landscape. The orange lines...
    • 21 Sep 2017

    3 Ways to Improve Packaging Line Flexibility for Increased Production

    You only have to walk down a supermarket isle to appreciate the diversity in the packaged goods we purchase. What was once a choice of glass jars or cans for many products now includes re-sealable bags, individual packaged servings, packaging made with recyclable feedstock, etc. Consumers, with their busy on-the-go lives, are creating this demand for convenience. Manufacturers providing these packaged products are...
    • 23 Aug 2017

    Pharmaceutical Wireless Instrumentation Retrofits

    Many industries have benefitted from the use of wireless instrumentation, but how about the pharmaceutical and biotech manufacturing industries? Are there applications which might improve the performance of their operations? In a Pharmaceutical Manufacturing article, Retrofitting Pharmaceutical Processes with WirelessHART Instrumentation , Emerson’s Michalle Adkins and Dan Carlson describe ways that these additional...
    • 29 Jun 2017

    Improving Batch Manufacturing Workflows and Recordkeeping

    The pharmaceutical and biotechnology manufacturing industries are challenged with errors in manual entries in the production process, getting batches right the first time, reaching final signoff for batch release, and managing the data accumulated throughout the production process. I caught up with Emerson’s Mary Sowders about some of these challenges and the way they are being addressed. Mary shared with me...
    • 26 Jun 2017

    Improving Pharmaceutical and Biotech Plant Utility Performance

    For pharmaceutical and biotech manufacturers, the use of steam, heating and air conditioning systems, water and other utilities are an important part of the manufacturing process. Efficient and reliable operations for these plant utilities is very important. In a Pharmaceutical Manufacturing article, Monitoring Plant Utilities for Operational Excellence , Emerson’s Michalle Adkins describes how additional measurements...
    • 5 Jun 2017

    Enabling Right-the-First-Time Manufacturing

    Quality and compliance are indispensable in pharmaceutical and biopharmaceutical manufacturing processes. In a Pharmaceutical Manufacturing magazine article, Crazy About Quality and Compliance? , Emerson’s Michalle Adkins shares how organizational engagement, technologies and work practices must come together for safe, efficient and profitable manufacturing. Michalle opens sharing her experiences in pharmaceutical...
    • 4 May 2017

    Improving Raw Material Management Productivity

    For manufacturers in highly-regulated industries, such as pharmaceutical and biopharmaceutical manufacturing, it is critical to keep track of raw materials as part of the production records. To minimize or avoid waste, it’s also important to use the first-to-expire raw materials from inventory. I caught up with Emerson’s Lynn Richard about his experiences to help a manufacturer solve this challenge and...
    • 24 Apr 2017

    Challenge of Designing PCS-Driven MES Architectures for a Greenfield Facility

    Author: Jonathan Lustri I have previously written about a design strategy where the process control system (PCS) is the primary system driving all procedural batch activity within a pharmaceutical process. In this architecture, the PCS ISA-88 procedural model must execute the both automated procedures and call the manufacturing execution system (MES) workflows to be executed when they are needed by the process. The...
    • 17 Apr 2017

    Efficient Technology Transfer across Life Sciences Product Development Lifecycle

    Pharmaceutical and biotech manufacturers are challenged with bringing new medicines and drug compounds efficiently through the development process to provide returns on these investments before exclusivity expires. In a Pharmaceutical Manufacturing article, Tech Transfer: Let’s Take It from the Top , Emerson’s Bob Lenich highlights the importance of a top down approach to technology transfer across the...
    • 5 Apr 2017

    Big Data and Process Analytics for Continued Process Verification

    A biological drug is defined as a: …substance that is made from a living organism or its products and is used in the prevention, diagnosis, or treatment of cancer and other diseases. Biological drugs include antibodies, interleukins, and vaccines. The market for biological drugs continues to rapidly grow. In fact, in China alone, there were 201 Biological New Drug Applications (NDAs) in 2016, a 32% increase...
    • 24 Mar 2017

    Automating Bioprocess Single-Use Systems

    For those not in the pharmaceutical and biotech manufacturing industries, if you ever visit one of these facilities you’ll be struck by the clean, shiny stainless steel vessels and piping. Given the importance of hygiene in the production of medicines, most processes include clean-in-place (CIP) and sterilize-in-place operations (SIP). The capital costs and ongoing time requirements for this stainless-steel equipment...
    • 14 Mar 2017

    Capital Project Efficiency-Operational Flexibility-Product Lifecycle Efficiency at Interphex

    Author: Michalle Adkins At the March 21-23 Interphex 2017 , Emerson exhibitor staff will be discussing three main themes: delivering capital projects on time with lower risk; comprehensive automation solutions for flexible, single-use facilities; and improving efficiency across the product lifecycle. Life Sciences companies are expanding globally in order to provide life-saving or life-enhancing solutions to more...
    • 26 Jan 2017

    Best Practices Specifying MES Workflows for Life Sciences Projects

    Author: Jonathan Lustri Manufacturing Execution System (MES) Life Sciences projects can be costly and be a challenge to keep in control. The biggest contributor to these challenges are the defining and design of manufacturing workflows. A Workflow is an MES procedural object used to replace the paper batch record. And for greenfield projects in particular, this can be a challenge. In order to define best practices...
    • 10 Jan 2017

    Measurement Repeatability in CIP and SIP Operations

    One only has to do a Google image search on pharmaceutical equipment to see the clean, sanitary conditions required for pharmaceutical and biopharmaceutical processing. The measurement instrumentation must be able to handle the tough conditions when cleaning and sanitization operations are performed. In a Pharmaceutical Manufacturing article, Ensuring Batch-to-Batch Repeatability in Sanitary Processes , Emerson’s...
    • 10 Nov 2016

    Pharmaceutical and Biotech Manufacturing Data Integrity

    The integrity of the data behind the production of pharmaceutical products is paramount. In recent years, the U.S. Food & Drug Administration (FDA) has increasingly observed data integrity related Current Good Manufacturing Practices (CGMP) violations during CGMP inspections. At the recent Emerson Exchange conference, Emerson’s Michalle Adkins co-moderated the Life Sciences Industry Forum session with experts...
    • 13 Oct 2016

    Pharmaceutical and Biotech Automation Knowledge Exchange

    The pharmaceutical and biopharmaceutical industries have been interpreting recent FDA draft guidance— Data Integrity and Compliance With CGMP Guidance —and exploring new areas such as continuous manufacturing. The Emerson Life Sciences team has a full program of forums, workshops and short courses available for manufacturers in the Life Sciences industries at to October 24-28 Emerson Exchange conference in Austin. ...
    • 17 Aug 2016

    Integrating Single Use Equipment More Easily with Control and Manufacturing Execution Systems

    One of the trends in the biopharmaceutical industries that have taken root over the past decade and a half is the use of single-use, disposable equipment in the manufacturing process. Prior to their use, these facilities relied on inflexible, hard-piped equipment. An American Pharmaceutical Review article highlights the benefits of single-use equipment: Single-use disposable devices and systems have reduced overall...
    • 4 Aug 2016

    Integrated Biometric Authentication in Electronic Records

    How many of you have more passwords than you can possibly remember? Count me in with the affirmatives. Biometric authentication is one way to overcome this large and growing problem. For process manufacturers and producers, especially those in highly...
    • 23 Jun 2016

    Trends in the Life Sciences Industry

    For pharmaceutical and biotech manufacturers, trends in the market place are driving changes in the way they have historically operated their production processes. I caught up with Emerson’s Michalle Adkins who shared these trends with me. She ...
    • 28 Apr 2016

    FDA Guidance for Data Integrity and Compliance

    Author: Michalle Adkins In April 2016, the FDA issued Data Integrity and Compliance With CGMP Guidance for Industry . This is on the heels of a lot of related 483s, warning letters , and more severe actions with respect to this issue. There are some ...
    • 7 Apr 2016

    Deploying Syncade Manufacturing Execution System in a Non-English Language

    Author: Jonathan Lustri I recently worked on a Syncade manufacturing execution system (MES) project where the system was deployed in Danish. Emerson executes all its projects with a global team and this one was no different. Our customer was Danish a...
    • 18 Mar 2016

    Continued Process Verification through Process Validation Stage 1, 2 and 3

    For pharmaceutical and biotech manufacturers, Continued Process Verification is: …the collection and analysis of end-to-end production components and processes data to ensure process is running under the state of control and product outputs a...
    • 15 Mar 2016

    Accurate and Repeatable Measurements in Pharmaceutical and Biotech Manufacturing

    A Pharmaceutical Manufacturing magazine study revealed that pharmaceutical and biotech manufacturers were challenged to achieve batch after batch repeatability. I came across a recently published whitepaper, Consistency and Repeatability Through Accu...
    • 3 Mar 2016

    Overcoming Pharmaceutical Continuous Manufacturing Challenges

    Why is there a movement in the pharmaceutical and biotech manufacturing industries to consider continuous manufacturing over traditional batch manufacturing processes? A 2012 U.S. Food & Drug Administration presentation, FDA Perspective on Contin...
    • 19 Feb 2016

    Batch Repeatability through Instrument Performance and Diagnostics

    Author: Kyle Knutson Batch repeatability is critical in pharmaceutical and biotech manufacturing. Variations between batches that cause deviations require extensive analysis, either in real-time or post-process, to identify how to control and minimi...