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Managing the Chain of Identity in Cell Therapeutics Manufacturing
Jim Cahill
Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. From a manufacturing perspective, each therapeutic batch must be perfect the first time — because each batch is produced for a specific patient. The next unique batch, for…
4 Jan 2018
Managing the Chain of Identity in Cell Therapeutics Manufacturing
Jim Cahill
Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. From a manufacturing perspective, each therapeutic batch must be perfect the first time — because each batch is produced for a specific patient. The next unique batch, for…
4 Jan 2018
Managing the Chain of Identity in Cell Therapeutics Manufacturing
Jim Cahill
Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. From a manufacturing perspective, each therapeutic batch must be perfect the first time — because each batch is produced for a specific patient. The next unique batch, for…
4 Jan 2018
Managing the Chain of Identity in Cell Therapeutics Manufacturing
Jim Cahill
Medicines produced by pharmaceutical and biotech manufacturers are manufactured in many ways. One particular type of treatment, cell therapy, is defined as : …the transplantation of human or animal cells to replace or repair damaged tissue. From a manufacturing perspective, each therapeutic batch must be perfect the first time — because each batch is produced for a specific patient. The next unique batch, for…
4 Jan 2018
Improving Batch Manufacturing Workflows and Recordkeeping
Jim Cahill
The pharmaceutical and biotechnology manufacturing industries are challenged with errors in manual entries in the production process, getting batches right the first time, reaching final signoff for batch release, and managing the data accumulated throughout the production process. I caught up with Emerson’s Mary Sowders about some of these challenges and the way they are being addressed. Mary shared with me that the…
29 Jun 2017
Improving Batch Manufacturing Workflows and Recordkeeping
Jim Cahill
The pharmaceutical and biotechnology manufacturing industries are challenged with errors in manual entries in the production process, getting batches right the first time, reaching final signoff for batch release, and managing the data accumulated throughout the production process. I caught up with Emerson’s Mary Sowders about some of these challenges and the way they are being addressed. Mary shared with me that the…
29 Jun 2017
Improving Batch Manufacturing Workflows and Recordkeeping
Jim Cahill
The pharmaceutical and biotechnology manufacturing industries are challenged with errors in manual entries in the production process, getting batches right the first time, reaching final signoff for batch release, and managing the data accumulated throughout the production process. I caught up with Emerson’s Mary Sowders about some of these challenges and the way they are being addressed. Mary shared with me that the…
29 Jun 2017
Improving Batch Manufacturing Workflows and Recordkeeping
Jim Cahill
The pharmaceutical and biotechnology manufacturing industries are challenged with errors in manual entries in the production process, getting batches right the first time, reaching final signoff for batch release, and managing the data accumulated throughout the production process. I caught up with Emerson’s Mary Sowders about some of these challenges and the way they are being addressed. Mary shared with me that the…
29 Jun 2017
Improving Raw Material Management Productivity
Jim Cahill
For manufacturers in highly-regulated industries, such as pharmaceutical and biopharmaceutical manufacturing, it is critical to keep track of raw materials as part of the production records. To minimize or avoid waste, it’s also important to use the first-to-expire raw materials from inventory. I caught up with Emerson’s Lynn Richard about his experiences to help a manufacturer solve this challenge and increase overall…
4 May 2017
Improving Raw Material Management Productivity
Jim Cahill
For manufacturers in highly-regulated industries, such as pharmaceutical and biopharmaceutical manufacturing, it is critical to keep track of raw materials as part of the production records. To minimize or avoid waste, it’s also important to use the first-to-expire raw materials from inventory. I caught up with Emerson’s Lynn Richard about his experiences to help a manufacturer solve this challenge and increase overall…
4 May 2017
Improving Raw Material Management Productivity
Jim Cahill
For manufacturers in highly-regulated industries, such as pharmaceutical and biopharmaceutical manufacturing, it is critical to keep track of raw materials as part of the production records. To minimize or avoid waste, it’s also important to use the first-to-expire raw materials from inventory. I caught up with Emerson’s Lynn Richard about his experiences to help a manufacturer solve this challenge and increase overall…
4 May 2017
Improving Raw Material Management Productivity
Jim Cahill
For manufacturers in highly-regulated industries, such as pharmaceutical and biopharmaceutical manufacturing, it is critical to keep track of raw materials as part of the production records. To minimize or avoid waste, it’s also important to use the first-to-expire raw materials from inventory. I caught up with Emerson’s Lynn Richard about his experiences to help a manufacturer solve this challenge and increase overall…
4 May 2017
Challenge of Designing PCS-Driven MES Architectures for a Greenfield Facility
Jim Cahill
Author: Jonathan Lustri I have previously written about a design strategy where the process control system (PCS) is the primary system driving all procedural batch activity within a pharmaceutical process. In this architecture, the PCS ISA-88 procedural model must execute the both automated procedures and call the manufacturing execution system (MES) workflows to be executed when they are needed by the process. The…
24 Apr 2017
Challenge of Designing PCS-Driven MES Architectures for a Greenfield Facility
Jim Cahill
Author: Jonathan Lustri I have previously written about a design strategy where the process control system (PCS) is the primary system driving all procedural batch activity within a pharmaceutical process. In this architecture, the PCS ISA-88 procedural model must execute the both automated procedures and call the manufacturing execution system (MES) workflows to be executed when they are needed by the process. The…
24 Apr 2017
Challenge of Designing PCS-Driven MES Architectures for a Greenfield Facility
Jim Cahill
Author: Jonathan Lustri I have previously written about a design strategy where the process control system (PCS) is the primary system driving all procedural batch activity within a pharmaceutical process. In this architecture, the PCS ISA-88 procedural model must execute the both automated procedures and call the manufacturing execution system (MES) workflows to be executed when they are needed by the process. The…
24 Apr 2017
Best Practices Specifying MES Workflows for Life Sciences Projects
Jim Cahill
Author: Jonathan Lustri Manufacturing Execution System (MES) Life Sciences projects can be costly and be a challenge to keep in control. The biggest contributor to these challenges are the defining and design of manufacturing workflows. A Workflow is an MES procedural object used to replace the paper batch record. And for greenfield projects in particular, this can be a challenge. In order to define best practices…
26 Jan 2017
Best Practices Specifying MES Workflows for Life Sciences Projects
Jim Cahill
Author: Jonathan Lustri Manufacturing Execution System (MES) Life Sciences projects can be costly and be a challenge to keep in control. The biggest contributor to these challenges are the defining and design of manufacturing workflows. A Workflow is an MES procedural object used to replace the paper batch record. And for greenfield projects in particular, this can be a challenge. In order to define best practices…
26 Jan 2017
Best Practices Specifying MES Workflows for Life Sciences Projects
Jim Cahill
Author: Jonathan Lustri Manufacturing Execution System (MES) Life Sciences projects can be costly and be a challenge to keep in control. The biggest contributor to these challenges are the defining and design of manufacturing workflows. A Workflow is an MES procedural object used to replace the paper batch record. And for greenfield projects in particular, this can be a challenge. In order to define best practices…
26 Jan 2017
Integrating Single Use Equipment More Easily with Control and Manufacturing Execution Systems
Jim Cahill
One of the trends in the biopharmaceutical industries that have taken root over the past decade and a half is the use of single-use, disposable equipment in the manufacturing process. Prior to their use, these facilities relied on inflexible, hard-piped equipment. An American Pharmaceutical Review article highlights the benefits of single-use equipment: Single-use disposable devices and systems have reduced overall…
17 Aug 2016
Integrating Single Use Equipment More Easily with Control and Manufacturing Execution Systems
Jim Cahill
One of the trends in the biopharmaceutical industries that have taken root over the past decade and a half is the use of single-use, disposable equipment in the manufacturing process. Prior to their use, these facilities relied on inflexible, hard-piped equipment. An American Pharmaceutical Review article highlights the benefits of single-use equipment: Single-use disposable devices and systems have reduced overall…
17 Aug 2016
Integrating Single Use Equipment More Easily with Control and Manufacturing Execution Systems
Jim Cahill
One of the trends in the biopharmaceutical industries that have taken root over the past decade and a half is the use of single-use, disposable equipment in the manufacturing process. Prior to their use, these facilities relied on inflexible, hard-piped equipment. An American Pharmaceutical Review article highlights the benefits of single-use equipment: Single-use disposable devices and systems have reduced overall…
17 Aug 2016
Integrated Biometric Authentication in Electronic Records
Jim Cahill
How many of you have more passwords than you can possibly remember? Count me in with the affirmatives. Biometric authentication is one way to overcome this large and growing problem. For process manufacturers and producers, especially those in highly regulated industries such as pharmaceutical and biopharmaceutical manufacturing, authenticated actions also need to be recorded to prove that the manufacturing process was…
4 Aug 2016
Integrated Biometric Authentication in Electronic Records
Jim Cahill
How many of you have more passwords than you can possibly remember? Count me in with the affirmatives. Biometric authentication is one way to overcome this large and growing problem. For process manufacturers and producers, especially those in highly regulated industries such as pharmaceutical and biopharmaceutical manufacturing, authenticated actions also need to be recorded to prove that the manufacturing process was…
4 Aug 2016
Integrated Biometric Authentication in Electronic Records
Jim Cahill
How many of you have more passwords than you can possibly remember? Count me in with the affirmatives. Biometric authentication is one way to overcome this large and growing problem. For process manufacturers and producers, especially those in highly regulated industries such as pharmaceutical and biopharmaceutical manufacturing, authenticated actions also need to be recorded to prove that the manufacturing process was…
4 Aug 2016
Automating Tank Farm Systems and Work Practices
Jim Cahill
Have you ever stopped to consider the path and ownership transfers your car’s gasoline or diesel took from the wellhead when it was still crude oil until you pumped it into your tank at the gas station? For the businesses involved in custody transfer process through the supply chain path, how accurate, reliable, safe and efficient were these transfers? In a Tanks & Terminals article, The Power of Automation , Emerson…
18 May 2016
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