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Understanding Servers, Converters and Gateways
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Digital Tools More Quickly Deliver Treatments to Patients
Jim Cahill
Imagine driving the wrong direction for hundreds of miles after a wrong turn, simply because you didn’t notice missing the exit. Overlooked deviations can cause a lot of frustration, whether during a drive or while executing a batch of pharmaceuticals. Detecting and recognizing a deviation or other problem while in process is called review by exception (RBE) and it can be done live. This is the main point of my article…
3 Dec 2020
Progressing with IIoT on the Cloud for Oil & Gas
Jim Cahill
For many E&P companies considering field automation, it may seem that installing a SCADA system will provide all the information, alarms and control you need to reach your goals, including boosting production and reducing costs. And SCADA does help, but not nearly as much as installing automation through the cloud. In this ever-increasing digital world, people and companies rely more and more on the cloud for data storage…
23 Oct 2020
Progressing with IIoT on the Cloud for Oil & Gas
Jim Cahill
For many E&P companies considering field automation, it may seem that installing a SCADA system will provide all the information, alarms and control you need to reach your goals, including boosting production and reducing costs. And SCADA does help, but not nearly as much as installing automation through the cloud. In this ever-increasing digital world, people and companies rely more and more on the cloud for data storage…
23 Oct 2020
Real-Time Adaptive Scheduling in Life Science Manufacturing
Jim Cahill
Pharmaceutical & Biopharmaceutical manufacturers face the continued challenge of how to achieve maximum capacity in their facilities. Often a facility does not achieve maximum design capacity due to hidden operational bottlenecks. One way to drive performance gains is to identify the causes behind this situation and operate as close to design specifications as is possible. At the Biomanufacturing World Summit, Emerson…
10 Mar 2020
Real-Time Adaptive Scheduling in Life Science Manufacturing
Jim Cahill
Pharmaceutical & Biopharmaceutical manufacturers face the continued challenge of how to achieve maximum capacity in their facilities. Often a facility does not achieve maximum design capacity due to hidden operational bottlenecks. One way to drive performance gains is to identify the causes behind this situation and operate as close to design specifications as is possible. At the Biomanufacturing World Summit, Emerson…
10 Mar 2020
Manufacturing Execution Systems in Drug Research and Development
Jim Cahill
The U.S. Food & Drug Administration (FDA) outlines the drug development process in five steps: Discovery and development Preclinical research Clinical trials FDA review FDA post-market safety monitoring Zuwei Jin I caught up with Emerson’s Zuwei Jin whom you may recall from earlier posts on the role of automation in the drug development process . Zuwei explained to me how manufacturing execution systems…
13 Feb 2019
Manufacturing Execution Systems in Drug Research and Development
Jim Cahill
The U.S. Food & Drug Administration (FDA) outlines the drug development process in five steps: Discovery and development Preclinical research Clinical trials FDA review FDA post-market safety monitoring Zuwei Jin I caught up with Emerson’s Zuwei Jin whom you may recall from earlier posts on the role of automation in the drug development process . Zuwei explained to me how manufacturing execution systems…
13 Feb 2019
Manufacturing Execution Systems in Drug Research and Development
Jim Cahill
The U.S. Food & Drug Administration (FDA) outlines the drug development process in five steps: Discovery and development Preclinical research Clinical trials FDA review FDA post-market safety monitoring Zuwei Jin I caught up with Emerson’s Zuwei Jin whom you may recall from earlier posts on the role of automation in the drug development process . Zuwei explained to me how manufacturing execution systems…
13 Feb 2019
Manufacturing Execution Systems in Drug Research and Development
Jim Cahill
The U.S. Food & Drug Administration (FDA) outlines the drug development process in five steps: Discovery and development Preclinical research Clinical trials FDA review FDA post-market safety monitoring Zuwei Jin I caught up with Emerson’s Zuwei Jin whom you may recall from earlier posts on the role of automation in the drug development process . Zuwei explained to me how manufacturing execution systems…
13 Feb 2019
Tracking Cell Therapy Chain of Identity
Jim Cahill
Cell therapy is when: …cellular material is injected into a patient; [1] this generally means intact, living cells . For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy . For manufacturers in the Life Sciences industry, making these therapies poses challenges since each batch is specific to a given patient. In this 2:25 YouTube video…
5 Nov 2018
Tracking Cell Therapy Chain of Identity
Jim Cahill
Cell therapy is when: …cellular material is injected into a patient; [1] this generally means intact, living cells . For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy . For manufacturers in the Life Sciences industry, making these therapies poses challenges since each batch is specific to a given patient. In this 2:25 YouTube video…
5 Nov 2018
Tracking Cell Therapy Chain of Identity
Jim Cahill
Cell therapy is when: …cellular material is injected into a patient; [1] this generally means intact, living cells . For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy . For manufacturers in the Life Sciences industry, making these therapies poses challenges since each batch is specific to a given patient. In this 2:25 YouTube video, Address…
5 Nov 2018
Tracking Cell Therapy Chain of Identity
Jim Cahill
Cell therapy is when: …cellular material is injected into a patient; [1] this generally means intact, living cells . For example, T cells capable of fighting cancer cells via cell-mediated immunity may be injected in the course of immunotherapy . For manufacturers in the Life Sciences industry, making these therapies poses challenges since each batch is specific to a given patient. In this 2:25 YouTube video, Address…
5 Nov 2018
Best Practice for MES-SAP interface Factory Acceptance Testing
Jim Cahill
Author: Jonathan Lustri Almost all Life Sciences manufacturing execution system (MES) projects include an interface to SAP, the enterprise resource management system . This interface is strategic in that this is how the business and production are tied together. It allows the manufacturing floor to be integrated with the business for cost accounting, material planning, and production planning. The integration transactions…
24 Sep 2018
Best Practice for MES-SAP interface Factory Acceptance Testing
Jim Cahill
Author: Jonathan Lustri Almost all Life Sciences manufacturing execution system (MES) projects include an interface to SAP, the enterprise resource management system . This interface is strategic in that this is how the business and production are tied together. It allows the manufacturing floor to be integrated with the business for cost accounting, material planning, and production planning. The integration transactions…
24 Sep 2018
Best Practice for MES-SAP interface Factory Acceptance Testing
Jim Cahill
Author: Jonathan Lustri Almost all Life Sciences manufacturing execution system (MES) projects include an interface to SAP, the enterprise resource management system . This interface is strategic in that this is how the business and production are tied together. It allows the manufacturing floor to be integrated with the business for cost accounting, material planning, and production planning. The integration transactions…
24 Sep 2018
Best Practice for MES-SAP interface Factory Acceptance Testing
Jim Cahill
Author: Jonathan Lustri Almost all Life Sciences manufacturing execution system (MES) projects include an interface to SAP, the enterprise resource management system . This interface is strategic in that this is how the business and production are tied together. It allows the manufacturing floor to be integrated with the business for cost accounting, material planning, and production planning. The integration transactions…
24 Sep 2018
Best Practices for Implementing a Process Control Driven MES System
Jim Cahill
Author: Jonathan Lustri I have previously been interviewed and written about a process control and MES [ Manufacturing Execution Systems ] architecture where the batch control logic within the process control system is the single procedural engine. It drives procedural logic and workflows executed by the MES system when called by the process control system. The benefit of this architecture is an overall lower cost…
21 Aug 2018
Best Practices for Implementing a Process Control Driven MES System
Jim Cahill
Author: Jonathan Lustri I have previously been interviewed and written about a process control and MES [ Manufacturing Execution Systems ] architecture where the batch control logic within the process control system is the single procedural engine. It drives procedural logic and workflows executed by the MES system when called by the process control system. The benefit of this architecture is an overall lower cost…
21 Aug 2018
Best Practices for Implementing a Process Control Driven MES System
Jim Cahill
Author: Jonathan Lustri I have previously been interviewed and written about a process control and MES [ Manufacturing Execution Systems ] architecture where the batch control logic within the process control system is the single procedural engine. It drives procedural logic and workflows executed by the MES system when called by the process control system. The benefit of this architecture is an overall lower cost…
21 Aug 2018
Best Practices for Implementing a Process Control Driven MES System
Jim Cahill
Author: Jonathan Lustri I have previously been interviewed and written about a process control and MES [ Manufacturing Execution Systems ] architecture where the batch control logic within the process control system is the single procedural engine. It drives procedural logic and workflows executed by the MES system when called by the process control system. The benefit of this architecture is an overall lower cost…
21 Aug 2018
Moving to Electronic Batch Records
Jim Cahill
Yesterday we highlighted advancements in exception management technology for pharmaceutical and biopharmaceutical manufacturers. Exception management is one element in an electronic batch record (EBR) . Other elements for the EBR which also have high data integrity requirements include equipment management, material management and batch record process flow and recipe management. In a PharmTech article, Making the…
30 May 2018
Moving to Electronic Batch Records
Jim Cahill
Yesterday we highlighted advancements in exception management technology for pharmaceutical and biopharmaceutical manufacturers. Exception management is one element in an electronic batch record (EBR) . Other elements for the EBR which also have high data integrity requirements include equipment management, material management and batch record process flow and recipe management. In a PharmTech article, Making the…
30 May 2018
Moving to Electronic Batch Records
Jim Cahill
Yesterday we highlighted advancements in exception management technology for pharmaceutical and biopharmaceutical manufacturers. Exception management is one element in an electronic batch record (EBR) . Other elements for the EBR which also have high data integrity requirements include equipment management, material management and batch record process flow and recipe management. In a PharmTech article, Making the…
30 May 2018
Moving to Electronic Batch Records
Jim Cahill
Yesterday we highlighted advancements in exception management technology for pharmaceutical and biopharmaceutical manufacturers. Exception management is one element in an electronic batch record (EBR) . Other elements for the EBR which also have high data integrity requirements include equipment management, material management and batch record process flow and recipe management. In a PharmTech article, Making the…
30 May 2018
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