Activity

  • DeltaV Spectral PAT for Life Sciences Podcast

    Jim Cahill
    Process Analytical Technology, or PAT , was introduced by the U.S. Food & Drug Administration back in 2004. The purpose of this guidance was: …to describe a regulatory framework (Process Analytical Technology, (PAT) that will encourage the voluntary development and implementation of innovative pharmaceutical development, manufacturing, and quality assurance. Raman spectrometers perform spectral analysis to enable…

  • Micro Motion™︎ G-Series: Precision in a Compact Package

    Jim Cahill
    Over many years working with end users who are trying to solve challenging flow measurement problems, I’ve often suggested that a Coriolis mass flow meter is exactly the technology solution needed, but in some cases an alternative is preferred for a variety of reasons. Just to review, let’s mention a few of the reasons why Micro Motion Coriolis Mass Flow Meters are so versatile in many straightforward and difficult…

  • Ultrasonic Innovation: The Story of IrriFlex®︎

    Jim Cahill
    Have you ever wondered what goes into making a root canal procedure as safe and effective as possible? For dentists, a key tool is the irrigation cannula, a small tube that delivers cleaning solutions during the procedure. While traditionally, metal cannulas have been used to this purpose, a Swiss company, Produits Dentaire SA ( PD-Dental ), envisioned a better way: a flexible plastic cannula named IrriFlex that could…

  • Smaller Batches Still Have Big Needs

    Jim Cahill
    There’s no question that today’s life sciences landscape is changing dramatically. As new personalized medicine solutions emerge, companies are rapidly changing scale to include more multi-product manufacturing facilities. Many of these facilities are manufacturing treatments in much smaller batches. While many of the requirements around developing smaller-batch treatments are the same, the market does have its own…

  • Data Integrity in Life Sciences Podcast

    Jim Cahill
    For pharmaceutical and biopharmaceutical manufacturers, the data that accompanies the production is as critical as what is being produced. The integrity of this data is paramount for the successful release of the products for sale that comply with all regulatory requirements. In this Emerson Automation Experts podcast , Michalle Adkins and Hilary Mills-Baker join me to discuss the challenges of achieving the required…

  • Retrofitting a New Transmitter to an Existing Micro Motion™︎ Coriolis Flow Meter Adds New Capabilities

    Jim Cahill
    Most of us know someone who carries a really old smartphone, or maybe just a cellphone. Some people do this deliberately as a statement, but others just can’t be bothered with doing an upgrade. Everybody doesn’t need the latest whiz-bang technology, but many truly useful capabilities don’t work on old platforms. Such can be the reality in many industrial environments, where the pinnacle of achievement for some is still…

  • Achieving Data Integrity, Quality & Compliance in Manufacturing

    Jim Cahill
    In highly regulated industries such as pharmaceuticals and biopharmaceuticals, the data accompanying production is critical to the successful release of products. In a recent webinar, Achieve Data Integrity, Quality & Compliance Across Your Organization , Emerson’s Michalle Adkins and Hilary Mills-Baker share how data integrity means complete, consistent, accurate data throughout its lifecycle. This webinar is now available…

  • Improving Recipe Management by Implementing FAIR Principles

    Jim Cahill
    BioPhorum recently published an excellent paper, Data governance needs in biomanufacturing: a position paper . This paper proposes adopting the FAIR principles for data management, meaning that data must be F indable, A ccessible, I nteroperable, and R eusable . As stated in the paper: Adopting these principles is a potentially transformational opportunity for the life sciences industry, one that could fundamentally…

  • Exploring the Ways to Improve the Efficiency of Solenoid and Miniature Valves for Homecare and Portable Medical Devices

    Jim Cahill
    By combining the flexibility of new and proven flow-control products with the engineering expertise offered by valve suppliers, control valves for home care medical devi ces can become more efficient than ever before. In this article by Paul Gant, he listed some of the factors to consider in order to control and overcome various challenges and meet the demands needed in the medical industry. One key aspect to consider…

  • Exploring the Ways to Improve the Efficiency of Solenoid and Miniature Valves for Homecare and Portable Medical Devices

    Jim Cahill
    By combining the flexibility of new and proven flow-control products with the engineering expertise offered by valve suppliers, control valves for home care medical devi ces can become more efficient than ever before. In this article by Paul Gant, he listed some of the factors to consider in order to control and overcome various challenges and meet the demands needed in the medical industry. One key aspect to consider…

  • Driving Operational Improvements with a Rugged PAT Model Infrastructure

    Jim Cahill
    Real-time manual sampling has been a tried-and-true manufacturing practice for decades. But this antiquated approach has been subject to the risk of human error, time-sensitive, and time-consuming. Today’s digital technologies have enabled manufacturers to automate and improve this process. At the IFPAC-2023 meeting , Emerson’s Bruce Greenwald and Aspen Technology’s Geir Rune Flåten teamed together to present, Deploying…

  • Life Sciences Single-Use Instrumentation Trends

    Jim Cahill
    For most industries, scaling up with large batch sizes and high-volume production equipment is the best way to gain efficiency. This has also been true for production of many life sciences drugs, but portions of the industry are shifting toward creating smaller runs of “personalized drugs,” especially biologics, targeting smaller population segments. In our June 2023 article in Pharmaceutical Processing World , titled…

  • Unshackle Innovation with One Click Tech Transfer

    Jim Cahill
    Most people have heard the adage that, “COVID changed everything.” However, few people, when presented with that idea, think that any of those changes were positive. But we often forget that in the span of eight short months, the world saw a wide array of innovators and manufacturers come together to deliver a vaccine—a process that typically takes upwards of 15 years. In his recent article in Industry Week magazine…

  • Life Sciences Digital Maturity – Know Where You Are to Know Where You Can Go

    Jim Cahill
    To know where you’re going, you have to know where you are, and operating a life sciences manufacturing facility is no exception. Pharmaceutical processors regularly have to take stock of their technological capacity to keep a finger on the pulse of the four main drivers of operational excellence: Pipeline acceleration – the capability to quickly bring new products to market. Flexible manufacturing – maintaining…

  • Prototype Sensing Technologies are at the Forefront of Innovation

    Jim Cahill
    On June 4-7, experts in process analytical technology (PAT) gathered for the 2023 IFPAC conference . While there, they discussed the latest developments in PAT , quality by design, and overall process monitoring and control within the pharmaceutical, biotechnology, food, chemical, petrochemical, and related industries. Once again, Emerson experts were in attendance. Ye Lin and Ben Arriola presented new technologies…

  • Data-Driven Culture Drives Maintenance and Reliability Results

    Jim Cahill
    Life sciences organizations are not short on data. Most plants already have many sensors in place to drive operational data to the control system so operators always know exactly what is happening at any given moment of production. Operations teams know that good data is essential to Good Manufacturing Practice, and, as such, they treat it with the reverence it deserves. In her recent article in Pharmaceutical Processing…

  • Digital Solutions for Process Development, Tech Transfer and Manufacturing

    Jim Cahill
    Last week, IFPAC 2023 was held in Maryland. If you’re unfamiliar with IFPAC, here is a description from their website. IFPAC is the essential meeting place for the latest developments in Process Analytical Technology…PAT, Quality by Design…QbD, and overall process monitoring & control within the Pharmaceutical, Biotechnology, Food, Chemical, Petrochemical & related industries. Emerson’s Michalle Adkins and AspenTech…

  • Traceability Across the Entire Drug Development Pipeline

    Jim Cahill
    Recently, as cell and gene therapies have begun to emerge in the life sciences manufacturing landscape, an important concept has begun to draw attention: traceability. However, it is important to remember that traceability was critical long before today’s most cutting-edge therapies began development. Traceability has been essential in the manufacture of nearly every treatment, both in process definition and in product…

  • Better Treatment—For the Earth, and its People

    Jim Cahill
    It can be hard to keep up with the many rapid changes occurring in the life sciences industry these days. In an effort to embrace improved speed to market, sustainability , and quality, life sciences manufacturers are employing a wide range of software and technologies that only ten short years ago might have been considered science fiction. To help filter these many trends and give readers a glimpse into where the…

  • Four Pillars of Life Sciences Speed to Market

    Jim Cahill
    People are more aware than ever of the many amazing ways new treatments can improve their lives. As a result, life sciences companies are under more pressure than ever to safely deliver new, innovative treatments to market to satisfy customer demand. The key to accelerating that pipeline is based around four pillars of digitalization that Emerson experts Michalle Adkins and Karen Fung share in a recent Q&A in BioPharma…

  • Smart Maintenance Practices in Biopharmaceutical Manufacturing

    Jim Cahill
    As the Industrial Internet of Things enables more and more wireless instrumentation, the ability to transform maintenance practices to become more predictive grows. While companies in several industries have moved to predictive maintenance practices, companies in other sectors have been somewhat slower to adopt them. In a new paper published by the BioPhorum organization, Smart Maintenance Architecture: A Data-Driven…

  • What Is Emerson’s Rapid Engineered Solutions Program?

    Jim Cahill
    Rapid Engineered Solutions help analytical and medical equipment manufacturers accelerate the fluid handling design and engineering phase of new product development. Are you an analytical or medical OEM design engineer struggling with compressed product development timelines? Do you need a rapid solution to complex fluidic system challenges? The Rapid Engineered Solutions program from Emerson is the perfect solution…

  • What Is Emerson’s Rapid Engineered Solutions Program?

    Jim Cahill
    Rapid Engineered Solutions help analytical and medical equipment manufacturers accelerate the fluid handling design and engineering phase of new product development. Are you an analytical or medical OEM design engineer struggling with compressed product development timelines? Do you need a rapid solution to complex fluidic system challenges? The Rapid Engineered Solutions program from Emerson is the perfect solution…

  • Embedded Spectral Process Analytic Technology

    Jim Cahill
    Effective quality assurance processes are essential in pharmaceutical and biopharmaceutical manufacturing processes. Deploying Process Analytical Technologies (PAT) is one way these manufacturers have driven business improvements. Pharma Manufacturing magazine’s Pharma Innovation Awards highlights the technologies and systems driving improvements across manufacturing operations. Their December 2022 article, Pharma Innovation…

  • Improving Digital Maturity is Key to Life Sciences Success

    Jim Cahill
    In just the last 10 years, biopharmaceutical supply chains have changed dramatically. The single-source manufacturing model is becoming much rarer, making way for multi-enterprise manufacturing collaborations and partnerships to better meet the changing needs of the life sciences marketplace. In collaboration with other life sciences leaders, Emerson’s Michalle Adkins contributed to a BioPhorum paper outlining a vision…

This is the official online community site of the Emerson Global Users Exchange, a forum for the free exchange of non-proprietary information among the global user community of all Emerson Automation Solution's products and services. Our goal is to improve the efficiency and use of automation systems and solutions employed at members’ facilities by sharing our knowledge, experiences, and application information.

User Groups | World Areas | Community Guidelines | Legal Information | Privacy Policy | Contact Community Manager

Website translation provided by Website Translator

© 2015-2022 Emerson Global Users Exchange. All rights reserved.